Intraventricular haemorrhage in a fetus with cerebral cytomegalovirus infection

Cytomegalovirus (CMV) is the leading infectious cause of prenatal neurological damage, which is particularly severe when primary maternal infection occurs during the first 16 weeks of gestation, at the time of organ development and neuronal migration. Vascular involvement has been suggested to be among thepossible pathogenic mechanisms of virus-induced pathology, in addition to direct viral effects. We report on a fetus with cerebral CMV infection, which had intraventricular haemorrhage, together with oligohydramnios and hyperechogenic bowel, following maternal primary CMV infection. Copyright © 2002 John Wiley & Sons, Ltd.     

Waste management modeling by MARKAL model: A case study for Basilicata Region

Air pollution is one of the most pressing environmental problems which affects likewise urban, industrial and rural areas. Environmental planners, regulators and decision makers need reliable, scientifically based tools to find out strategies for controlling air pollution in a cost-effective way, taking into account the whole productive system. In this framework the basic elements of energy-environmental planning have to be extended to include also waste processing technologies amongst the usually considered pollution sources. Bottom-up optimizing models, based on linear programming techniques and customized for specific cases, represent a powerful tool in energy-environmental management. This paper focuses on the integrated modeling of material flows and energy system performed on a local scale case study (Basilicata Region, Southern Italy) using the linear programming model IEA-MARKAL. We have evaluated the feasibility of the model in representing the waste management system to estimate the environmental impact of the waste processing technologies in the context of the whole productive system. A sensitivity analysis has been carried out to emphasize the connections between tariffs, waste disposal technologies assessment and atmospheric emissions. This revised version was published online in July 2006 with corrections to the Cover Date.     

Increased levels of polychlorobiphenyls in Italian women with endometriosis

Endometriosis has been hypothesised to be linked to persistent and toxic organochlorinated chemicals. Dioxins and dioxin-like compounds have in particular been associated with the disease, mainly on the basis of experimental studies. Data in women are conflicting. A case-control study on 80 Italian nulliparous women of reproductive age was carried out to assess whether there is a correlation between the presence of endometriosis and blood levels of polychlorobiphenyls (PCBs), a family of ubiquitary environmental pollutants which comprises congeners with dioxin-like activity. Higher levels of PCBs were found in women with endometriosis. A mean cumulative value of 410 ng g(-1), lipid base, was found in cases versus the value of 250 ng g(-1) observed in the control group (odds ratio for upper tertile 4.0, CI 95% 1.3-13; p = 0.0003). PCB increase involved both dioxin-like (PCBs 105, 118, 156, and 167) and non-dioxin-like congeners (PCBs 101, 138, 153, 170, 180).