Fetal lower urinary tract obstruction: What should we tell the prospective parents?

Fetal lower urinary tract obstruction (LUTO), which often results in marked perinatal morbidity and mortality, is caused by a heterogeneous group of anatomical defects that lead to blockage of the urethra. The classic prenatal presentation of LUTO includes megacystis with hydronephrosis. While mild forms of the disease can be associated with favorable outcomes, more severe disease commonly leads to dysplastic changes in the fetal kidneys, and ultimately oligohydramnios, which can result in secondary pulmonary hypoplasia and renal failure at birth. The aim of this review is to provide practitioners with a general overview of the diagnosis and treatment of LUTO based on disease severity, along with some points to consider when counseling prospective parents of fetuses with this condition.     

Is there a role for fetal interventions in gastroschisis management? – An updated comprehensive review

We conducted a comprehensive evidence-based review on the epidemiology and current standard of care of gastroschisis management as well as the pathophysiology, rationale and feasibility of fetal therapy as a viable alternative. Gastroschisis is a periumbilical abdominal wall defect characterized by abdominal viscera herniation in utero. It affects 4 in 10 000 live births, but the prevalence has steadily increased in recent years. Gastroschisis is typically diagnosed on routine second-trimester ultrasound. The overall prognosis is favorable, but complex gastroschisis, which accounts for about 10% to 15% of cases, is associated with a higher mortality, significant disease burden and higher healthcare costs due to long- and short-term complications. The current standard of care has yet to be established but generally involves continued fetal surveillance and multidisciplinary perinatal care. Postnatal surgical repair is achieved with primary closure, staged silo closure or sutureless repair. Experimental animal studies have demonstrated the feasibility of in utero closure, antiinflammatory therapy and prenatal regenerative therapy. However, reports of early preterm delivery and amnioinfusion trials have failed to show any benefit in humans. Further experimental studies and human trials are necessary to demonstrate the potential benefit of fetal therapy in gastroschisis.     

Recapitulating potential environmental and industrial applications of biomass wastes

Journal of Material Cycles and Waste Management - The generation of biomass wastes is a huge concern as they have to be properly managed to ensure environmental wellbeing. This article examined...     

Respiratory,hepatic, renal,and hematological disorders among adolescent females environmentally exposed to pesticides,Menoufia governorate,Egypt

Environmental Science and Pollution Research - Adolescent females are often environmentally exposed to pesticides by living near agricultural fields, by using pesticides at home, or by having...     

The Seasonal Variation of the Concentrations of Ozone, Sulfur Dioxide, and Nitrogen Oxides in Two Nigerian Cities

A combination of multivariate statistical methods including factor analysis, principal component analysis, principal component regression, and multiple linear regression (MLR) were employed to evaluate the influence of seasons on the concentrations of ozone, sulfur (IV) oxide, and oxides of nitrogen in ambient air of Nigerian cities of Lagos and Ilorin. The former city is located in the coastal area, and it is highly congested with a high intensity of marine, vehicular, and industrial activities, and the latter city is a medium size town, located in the central guinea savannah zone of Nigeria. Samples were collected using a high-volume sampler from near the ground at various sites of diverse human and industrial activities, during wet and dry seasons from 2003 to 2006. The PCA reveals three distinct groupings during the day for all data, which is a reflection of different factors contributing to the atmospheric chemistry of these cities. The predicted ozone concentration values by MLR agree fairly well with the measured data. The dependence of ozone on meteorological parameters including relative humidity, air temperature, and sun exposure and the precursor pollutants depends on weather and the anthropogenic activities. The results for the two cities indicate that reduction in the level of NO₂ is accompanied by an increase in the level of ozone, suggesting the interconversion between the two via photochemical activity.     

Use of collective action for land accessibility among settled Fulani agro-pastoralists in southwest Nigeria

Having identified the use of collective action in gaining access to land in an earlier study, this study examined the forms of collective action being utilised by settled pastoralists in southwest Nigeria for land accessibility and use. The justification for this lies mainly on the optimism of the group theory that individuals with common interests would voluntarily act to further those interests. Six Fulani communities were selected purposively and data were collected from 120 settled agro-pastoralists. Interviews and focus group discussions were used to generate data on social features, livelihoods and collective action. Nine forms of collective action were identified, which were based on social networks and organised effort towards peaceful co-existence. Most of the collective action were rated effective by pastoralists in enhancing their land access. However, using the complete model with the Logit link function in the ordinal regression procedure, the study identified five of the collective actions with a higher probability (P < 0.05) of removing land restrictions, which were forms of use, farm size, grazing distance, grazing fields and land title restrictions. The most relevant problems to the effectiveness of collective action in the study area were the unwillingness of host communities and the non-participation of pastoralists. It is, therefore, recommended that settled pastoralists invest more on social networks in order to build stronger linkages with pastoral and host communities. This will enhance the ability to engage positively in the spheres of market and civil society. The organised efforts for peaceful coexistence will reduce the incidence of internal conflict.     

Urbanisation Without Development: Environmental and Health Implications in African Cities

Sustainable development advocates for a balance between socio-economic development and the environment in the pursuit of human advancement. In Africa, high population growth and inadequate infrastructure in urban areas exert pressure on the environment and this threatens the health and wellbeing of urban residents. The population of the African continent until the 1960s was predominantly rural. This scenario has taken a swift turn and some of the major shifts in the global urbanisation process are taking place on the continent. Factors including natural increase in the population, rural–urban migration, strife and hunger leading to the internal displacement of populations have exacerbated the urbanisation process in Africa. The situation has been worsened by the imposition of Western development policies, including structural adjustment programmes on African nations, which has eroded the subsistence base of rural agricultural communities and further ignited rural urban migration. The failure of industry to absorb the increasing labour force has created massive unemployment and deepening poverty crisis in urban centres. Inadequate provision of infrastructure and services to meet the growth in urban populations has resulted in inefficient spatial development of urban centres, the proliferation of squatter settlements, inadequate basic amenities including potable water, sanitation and waste disposal. Poor environmental sanitation has resulted in the upsurge of infectious diseases and deteriorating urban health. Urban populations in Africa are also the worst affected by newly emerging diseases, particularly HIV/AIDS. The poor bear a disproportionately large share of the problems due to their particular vulnerability to environmental and health risks. Readers should send their comments on this paper to: BhaskarNath@aol.com within 3 months of publication of this issue.     

Effect of green marketing mix,green customer value,and attitude on green purchase intention: evidence from the USA

Environmental Science and Pollution Research - The undertaken research examines the impact of green attitude, green customer value (e.g., environmental image and perceived value), and green...