Overall and local movement speeds during fire drill evacuations in buildings up to 31 stories

The time that it takes an occupant population to reach safety when descending a stairwell during building evacuations is typically described by measurable engineering variables such as stairwell geometry, speed, density, and pre-evacuation delay. In turn, engineering models of building evacuation use these variables to predict the performance of egress systems for building design, emergency planning, or event reconstruction. As part of a program to better understand occupant movement and behavior during building emergencies, the Engineering Laboratory at the National Institute of Standards and Technology (NIST) has been collecting stairwell movement data during fire drill evacuations of office buildings. These data collections are intended to provide a better understanding of this principal building egress feature and develop a technical foundation for future codes and standards requirements. To date, NIST has collected fire drill evacuation data in eight office building occupancies ranging from 6 to 62 stories in height that have included a range of stairwell widths and occupant densities.While average movement speeds in the current study of 0.48 m/s ± 0.16 m/s are observed to be quite similar to the range of literature values, local movement speeds as occupants traverse down the stairwell are seen to vary widely within a given stairwell, ranging from 0.056 m/s to 1.7 m/s. These data should provide confirmation of the adequacy of existing literature values typically used for occupant movement speeds or provide updated values for future analyses.     

不同碳源条件下草菇内切型纤维素酶基因（eg1）转录表达的分析

利用Northernblot方法分析了不同碳源条件下草菇切型纤维素酶基因(eg1)的表达.结果发现,在含有纤维素的液体培养基中生长10d,eg1在草菇菌丝中有高效表达;纤维二糖、α-乳糖、β-乳糖,也能诱导eg1的表达,但和纤维素相比,eg1的表达量相对较低,并且它们的诱导效应在加入这类糖12h后迅速减弱;槐糖和龙胆二糖的诱导作用非常弱.在天然稻草为基质的固体栽培料生长时,草菇eg1的表达和草菇菌丝生长与出菇相对应,在菌丝生长期(d8)可见eg1的表达,d12时菌丝已长满,表达减弱,在出菇及菇体的分化及增大期,eg1的表达量逐渐增强,在成熟期达到最高水平;表明在草菇菇体发育中需要更多碳源及能源的补充,eg1在这方面起着非常重要的作用.图4参14     

Erionite series minerals: mineralogical and carcinogenic properties

Erionite is a human and animal carcinogen and one of the most toxic minerals known. Erionite deposits have been reported in many countries; however, it is only in the area of three villages of Cappadocia, Turkey, that environmental exposure to erionite has been demonstrated to be the cause of an epidemic of the disease mesothelioma. In the USA, no cases of mesothelioma have been reliably proven to be the result of erionite exposure, though the possibility exists. Erionite samples from three villages of the Cappadocia region were characterized mineralogically and compared with three different standards from the USA. Micro morphological details of erionite minerals using a high-resolution field-emission SEM showed that microstructures of "bundles", "fibers", and "fibrils" are important physical properties of fibrous erionite minerals. Typical lung burden of erionite and asbestos fibers were compared in terms of number of fibers. Assuming the lung burden of fibers in a human mesothelioma victim is about 1 mg, and the hazardous fibers are approximately 1 mum in diameter and 10 mum long, that milligram contains approximately 40 million asbestos and 50 million erionite fibers. These microstructures of erionite minerals draw attention to the concepts of surface area or surface-area-to-volume ratio and their relationship to the carcinogenicity of the mineral. The larger surface area creates a wider platform for mineral-cell interaction and thus more possibilities of proliferative transformation of mesothelial cells. Consequently, understanding the exact mineralogical properties will help determination of the true carcinogenic mechanism(s) of the mineral for prevention and possibly treatment of malignant mesothelioma.     

Evaluating poverty–environment dynamics

Developing indicators to more effectively evaluate poverty–environment dynamics and inform policy is an urgent research priority. It is critical that these indicators are used in ways that accurately represent the relationship they are meant to inform. This article evaluates the theory and use of poverty–environment indicators, a relatively new tool developed to aid in the design and evaluation of poverty reduction strategies in the context of environmental change. We argue that while they have great potential, in their current form and use, poverty–environment indicators may contribute to critical misunderstandings of processes on the ground. These issues stem from a problematic and largely unacknowledged process of simplifying particular poverty–environment relationships. This article lays out the problematic character of this simplification process, and suggests how we might address these problems to create more useful understandings of poverty–environment dynamics to inform policy.     

不同碳源条件下草菇内切型纤维素酶基因(egl)转录表达的分析

利用Northern blot方法分析了不同碳源条件下草菇內切型纤维素酶基因(eg1)的表达.结果发现,在含有纤维素的液体培养基中生长10 d,eg1在草菇菌丝中有高效表达;纤维二糖、α-乳糖、β-乳糖,也能诱导eg1的表达,但和纤维素相比,eg1的表达量相对较低,并且它们的诱导效应在加入这类糖12 h后迅速减弱;槐糖和龙胆二糖的诱导作用非常弱.在天然稻草为基质的固体栽培料生长时,草菇eg1的表达和草菇菌丝生长与出菇相对应,在菌丝生长期(d 8)可见eg1的表达,d 12时菌丝已长满,表达减弱,在出菇及菇体的分化及增大期,eg1的表达量逐渐增强,在成熟期达到最高水平;表明在草菇菇体发育中需要更多碳源及能源的补充,eg1在这方面起着非常重要的作用. 图4 参14