Developmental response of Spodoptera litura Fab in response to plant extract of Desmostachya bipinnata (L.) and its effect on non-target organism,earthworm (Eisenia fetida)

Environmental Science and Pollution Research - Impact of chloroform extract of Desmostachya bipinnata was evaluated on armyworm Spodoptera litura (Lepidoptera: Noctuidae). The chloroform extract of...     

Protective effects of Flacourtia indica on doxorubicin-induced cardiotoxicity in rats

This study examined the cardioprotective activity of an ethanolic extract of Flacourtia indica (FI) against doxorubicin (DOX)-induced myocardial infarction (MI) in rats. Different phytoconstituents were identified by gas chromatography-mass spectroscopy. DOX is a chemotherapeutic agent which produces free oxygen radicals that result in serious dose-limiting cardiotoxicity. A DOX dose of 20?mg?kg^?1 body weight is used to bring significant changes in biochemical parameters, endogenous antioxidants, and moderate necrosis in the heart. The pretreatment with FI at two doses (250 and 500?mg?kg^?1) to DOX-treated rats significantly prevented the altered biochemical parameters such as serum marker enzymes serum glutamate-pyruvate transaminase, serum glutamate oxaloacetate transaminase, creatine phosphokinase, and lactate dehydrogenase, lipid profile such as low-density lipoprotein, very low-density lipoprotein, triglycerides, high-density lipoprotein, total cholesterol, and antioxidant parameters such as superoxide dismutase, glutathione, catalase, glutathione peroxidase, and malondialdehyde to near normal level. Serum urea, uric acid, and alkaline phosphate which are increased on DOX administration registered near normal values on pretreatment with FI. In conclusion, these data suggest that the ethanol extract of FI can prevent heart damage by DOX-induced MI in rats and this is likely mediated through its antioxidant activities.     

Larvicidal and repellent activity of N-methyl-1-adamantylamine and oleic acid a major derivative of bael tree ethanol leaf extracts against dengue mosquito vector and their biosafety on natural predator

Environmental Science and Pollution Research - Aegle marmelos (L.) Correa belongs to the family Rutaceae is generally known as “bael fruit tree” occuring across the south Asian...