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Both climatic and non-climatic factors affect surface water quality. Similar to its effect across various sectors and areas, climate change has potential to affect surface water quality directly and indirectly. On the one hand, the rise in temperature enhances the microbial activity and decomposition of organic matter in the river system and changes in rainfall alter discharge and water flow in the river ultimately affecting pollution dilution level. On the other hand, the disposal of organic waste and channelizing municipal sewage into the rivers seriously worsen water quality. This study attempts to relate hydro-climatology, water quality, and impact of climatic and non-climatic stresses in affecting river water quality in the upper Bagmati basin in Central Nepal. The results showed that the key water quality indicators such as dissolved oxygen and chemical oxygen demand are getting worse in recent years. No significant relationships were found between the key water quality indicators and changes in key climatic variables. However, the water quality indicators correlated with the increase in urban population and per capita waste production in the city. The findings of this study indicate that dealing with non-climatic stressors such as reducing direct disposal of sewerage and other wastes in the river rather than emphasizing on working with the effects from climate change would largely help to improve water quality in the river flowing from highly populated urban areas.  相似文献   
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Congenital heart defects (CHDs) are associated with neurodevelopmental (ND) delay. This study aims to assess evidence for impaired prenatal brain development, in fetuses with CHD. A systematical search was performed, and 34 studies evaluating the fetal brain [magnetic resonance imaging (MRI) or ultrasound] in isolated CHD were included (1990–2015). Data regarding cerebral abnormalities, head circumference growth and middle cerebral artery flow were extracted. Prenatal MRI was studied in ten articles (445 fetuses), resulting in a pooled prevalence of 18% (95%CI −6%; 42%) for combined structural and acquired cerebral abnormalities. Prenatal head circumference was studied in 13 articles (753 fetuses), resulting in a pooled z-score of −0.51 (95%CI −0.84; −0.18). Doppler was studied in 21 articles (1412 fetuses), resulting in a lower middle cerebral artery pulsatility index (z-score −0.70 95%CI −0.99; −0.41) in left-sided CHD only. We conclude that prenatal MRI and ultrasound demonstrate brain abnormalities, delay in head growth and brainsparing in subgroups of CHD. However, large MRI studies are scarce, and ultrasound data are biased towards severe and left-sided CHD. Long-term follow-up studies correlating prenatal findings with postnatal ND outcome are limited, and data are lacking to support counseling families regarding ND outcome based on prenatal findings suggestive of altered brain development. © 2016 John Wiley & Sons, Ltd.  相似文献   
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在二十世纪,各种合成化学品的使用有着令人注目的增长,特别是在制造产业和农业中.这些化学品中有许多后来显示出大量的不合乎需要的特性,包括在环境中的持久性,在食物链中生物放大的趋势,对于环境的负面影响.某些化学品也显示导致癌症或出生率下降.有些是非常危险的,即使在非常有限的暴露之后.  相似文献   
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In the western United States, livestock grazing often co-exists with recreation, cultural resource management and biodiversity protection on federal and state protected rangelands as well as on many local government open space areas. While the value of livestock grazing for managing rangeland vegetation to reduce fire fuel loads and improve wildlife habitat is increasingly recognized by resource management professionals, public concerns, and conflict between recreationist and livestock have led to reductions in public land grazing. Traditional public input methods yield a constrained picture of people’s attitudes toward cows and public land grazing. Public meetings, hearings, and surveys, the most commonly used mechanisms for public land managers to solicit public opinion, tend to foster participation of organized special interests or, in the case of surveys, focus on a specific topic. General public input is limited. This study explored the use of personal photography in social media to gain insight into public perceptions of livestock grazing in public spaces. Key findings of this study include that many recreationist in grazed San Francisco Bay Area parks shared views, interests, and concerns about cows and grazing on the photo-sharing website, FlickrTM that seldom show up at a public meeting or in surveys. Results suggest that social media analysis can help develop a more nuanced understanding of public viewpoints useful in making decisions and creating outreach and education programs for public grazing lands. This study demonstrates that using such media can be useful in gaining an understanding of public concerns about natural resource management.  相似文献   
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