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In this paper, the inventory-routing problem is studied for a closed-loop supply chain. This closed-loop supply chain considers suppliers, manufacturers, whole-sellers, and disposal centers. To formulate this problem, a mixed integer linear programming model is proposed. This mathematical model minimizes the total costs of the supply chain, including the fixed and variable costs of vehicles, and holding inventory costs of final products and scraps. The proposed model considers the road roughness degree, multi-path setting and the heterogeneous fleet of vehicles, which increases its flexibility and the quality of solutions. Then, two symmetry-breaking constraints are proposed to reduce the complexity of the mathematical model. In order to evaluate the integrity of the proposed model, 20 instances of different sizes are randomly generated and solved. Finally, a comprehensive sensitivity analysis is conducted with respect to five key features of the problem, such as the impact of the symmetry-breaking constraints on the CPU time, multi-path setting, fixed cost of vehicles, heterogeneous fleet of vehicles, and lost sales. The results indicate that the consideration of multi-path setting and the heterogeneous fleet of vehicles improves the quality of solutions significantly.  相似文献   
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The aim of the current research was to systematically review and summarize the studies that evaluated the concentration of lead (Pb) and cadmium (Cd) in cow milk in different regions of Iran and to perform a meta-analysis of the findings. Moreover, the non-carcinogenic and carcinogenic risks of Pb and Cd through milk consumption in adult and child consumers were assessed. As a result of a systematic search in the international and national databases between January 2008 and October 2018, 17 reports involving 1874 samples were incorporated in our study for meta-analysis. The pooled concentrations of Pb and Cd were estimated to be 13.95 μg mL−1 (95% CI 9.72–18.11 μg mL−1) and 3.55 μg mL−1 (95% CI − 2.38–9.48 μg mL−1), respectively, which were lower than the WHO/FAO and national standard limits. The estimated weekly intake (EWI) of Pb and Cd through consuming milk was 16.65 and 7 μg day−1 for adults of 70 kg and 45 and 34 μg day−1 for children of 26 kg, respectively, which was well below the risk values set by Joint FAO/WHO Expert Committee on Food Additives (JECFA). The maximum target hazard quotient values (THQs) of Pb and Cd were 5.55E−5 and 5.55E−5 for adults and 5.55E−5 and 5.55E−5 for children, respectively, which were lower than 1 value, suggesting that Iranian consumers are not exposed to non-carcinogenic risk through consuming milk. Moreover, the incremental lifetime cancer risk (ILCR) of Pb estimated to be 2.96E−04 in adults and 1.0E−03 in children, indicating that consumers in Iran are at threshold carcinogenic risk of Pb through consuming milk (ILCR > 10−4). Therefore, planning and policy making for the sustainable reduction of these toxic metals in milk, particularly in industrial regions of Iran, are crucial.  相似文献   
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Biochar is the bio-solid material produced by pyrolysis. The biochar properties are controlled by feedstock and pyrolysis variables. In this study, the impacts of these production variables on biochar yield and physicochemical properties including pH, cation exchange capacity (CEC), total organic carbon (TOC) content, surface area, and pore volume and size were investigated. Rice husk (RH) and oil palm empty fruit bunches (EFB) were used as biomass. The biochars were produced at temperature range of 300 to 700 °C, heating rate of 3 to 10 °C/min and retention time of 1 to 3 h. The pyrolysis conditions were optimized using response surface methodology (RSM) technique to maximize the values of the responses. Analysis of variance (ANOVA) of the results demonstrated that the data fitted well to the linear and quadratic equations. Temperature was found to be the most effective parameter on the responses followed by retention time and heating rate, sequentially. CEC, TOC, surface area, and pore characteristics were evaluated as biochar properties determining their sorption potential. The optimum conditions for the maximum values of the properties were temperatures of 700 and 493.44 °C and time of 3 and 1 h for RH and EFB biochars, respectively. Heating rate at 3 °C/min was found to be the best rate for both biochars. The structure of EFB biomass was more sensitive to heating than rice husk. The biomass type and the production variables were demonstrated as the direct effective factors on biochar yield and physicochemical properties.  相似文献   
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Landfills throughout the world are contributing to the global warming problem. This is due to the existence of the most important greenhouse gases (GHG) in landfill gas (LFG); namely, methane (CH4) and carbon dioxide (CO2). The aim of this paper is quantifying the total potential emissions, as well as the variation in production with time of CH4 from a proposed landfill (El Fukhary landfill) in the Gaza Strip, Palestine. Two different methods were adopted in order to quantify the total potential CH4 emissions; the Default methodology based on the intergovernmental panel on climate change (IPCC) 1996 revised guidelines and the Landfill Gas Emissions model (LandGEM V3.02) provided by the United States Environmental Protection Agency (EPA). The second objective of the study has been accomplished using the Triangle gas production model. The results obtained from both Default and LandGEM methods were found to be nearly the same. For 25 years of disposing MSW, El Fukhary landfill expected to have potential CH4 emissions of 1.9542 ± 0.0037 ×109 m3. Triangle model showed that the peak production in term of CH4 would occur in 2043; 28 years beyond the open year. Moreover, the model shows that 50 % of the gas will be produced approximately at the middle of the total duration of gas production. Proper control of Methane emissions from El Fukhary landfill is highly suggested in order to reduce the harmful effects on the environment.

Implications: Although, GHG emissions are extensively discussed in the developed countries throughout the world, it has gained little concern in the developing countries because they are forced most of the time to put environmental concerns at the end of their priority list. The paper shows that developing countries have to start recognizing their fault and change their way of dealing with environmental issues especially GHG emissions (mainly Methane and carbon dioxide). The authors estimated the potential methane emissions from a proposed central landfill that has been approved to be built in Palestine, a country that is classified as a developing country.  相似文献   

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Environmental Science and Pollution Research - Air pollution, particularly in urban areas, puts human health in danger and has adverse impacts on the built environment. It can accelerate the...  相似文献   
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