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141.
Aim of the present study is to determine the in-vitro cell cytotoxic effect of native and transformed cancer drugs (cyclophosphamide and etoposide) using three different white rot fungi (Ganoderma lucidum, Phanerochaete chrysosporium and Trametes versicolor). At 3, 6, 9, 12 and 15 days, experiments were done on a mouse monocyte macrophage cell line (Raw 264.7). After biodegradation, the altered compounds were found to be harmful to the Raw 264.7 cells. The maximal cytotoxicity of cyclophosphamide transformed products (TPs) were determined to be 2.4%, 7.3% and 7% respectively, against G. lucidum, P. chrysosporium and T. versicolor, respectively. With G. lucidum, P. chrysosporium and T. versicolor, the etoposide toxicity was 1.5%, 8% and 2.7% respectively. P. chrysosporium-mediated biodegradation resulted in the maximum toxicity, at 8%, on the 12th day for etoposide and 7.3% on the 3rd day for cyclophosphamide. After biodegradation by fungi, the toxicity of these two anticancer agents was reduced in the form of metabolites, but each fungus showed unique capacity for toxicity removal. 相似文献
142.
Kaushik CP Ravindra K Yadav K Mehta S Haritash AK 《Environmental monitoring and assessment》2006,122(1-3):27-40
Considering the mounting evidences of the effects of air pollution on health, the present study was undertaken to assess the ambient air quality status in the fast growing urban centres of Haryana state, India. The samples were collected for total suspended particulate matter (TSPM), respirable suspended particulate matter (PM10), sulfur dioxide (SO2), and oxides of nitrogen (NO2) during different seasons from 8 districts of Haryana during January, 1999 to September, 2000. The four types of sampling sites with different anthropogenic activities i.e. residential, sensitive, commercial and industrial were identified in each city. The ambient air concentration of TSPM and PM10 observed was well above the prescribed standards at almost all the sites. The average ambient air concentrations of SO2 and NO2 were found below the permissible limits at all the centres. Comparatively higher concentration of SO2 was observed during winter seasons, which seems to be related with the enhanced combustion of fuel for space heating and relatively stable atmospheric conditions. Air Quality Index (AQI) prepared for these cities shows that residential, sensitive and commercial areas were moderately to severely polluted which is a cause of concern for the residents of these cities. The high levels of TSPM and SO2 especially in winter are of major health concern because of their synergistic action. The data from Hisar city reveals a significant increase in the total number of hospital visits/admissions of the patients with acute respiratory diseases during winter season when the level of air pollutants was high. 相似文献
143.
Kumar Pankaj Mishra Vandana Yadav Shalu Yadav Archana Garg Shafali Poria Pankaj Farooqi Furqan Dumée Ludovic F. Sharma Radhey Shyam 《Environmental science and pollution research international》2022,29(40):60212-60231
Environmental Science and Pollution Research - A sectorial approach for assessing heavy metal pollution in rivers neglects the inter-relationship between its environmental compartments and thus... 相似文献
144.
Yadav Ishwar Chandra Devi Ningombam Linthoingambi 《Environmental science and pollution research international》2022,29(45):68216-68231
Environmental Science and Pollution Research - The fate of legacy and emerging flame retardants are poorly reported in developing countries, including India. Also, the positive matrix factorization... 相似文献
145.
Suleman Shariq Farooqui Asim Sharma Pradakshina Malhotra Nitesh Yadav Neelam Narang Jagriti Hasnain Md Saquib Nayak Amit Kumar 《Environmental science and pollution research international》2022,29(6):8091-8108
Environmental Science and Pollution Research - Viruses are the potential cause of several diseases including novel corona virus-19, flu, small pox, chicken pox, acquired immunodeficiency syndrome,... 相似文献
146.
Yadav Pratibha Yadav Anshul Labhasetwar Pawan Kumar 《Environmental science and pollution research international》2022,29(25):37204-37217
Environmental Science and Pollution Research - In this study, we synthesized recyclable Fe3O4-functionalized MIL101(Fe) chitosan composite beads for the removal of tetracycline (TC), doxycycline... 相似文献
147.
Sneha Yadav Yashas Shivamurthy Ravindra Thinley Tenzin Prabagar Jijoe Samuel Puttaiah Shivaraju Harikaranahalli 《Environmental science and pollution research international》2022,29(45):67969-67980
Environmental Science and Pollution Research - Antibiotics in water system pose a human health risk due to the rise of antibacterial activity in the environmental web. Advanced oxidation processes... 相似文献
148.
Environment, Development and Sustainability - As per the objective of the present experimental investigation, influence of various configurations of manifolds for optimum flow distribution in... 相似文献
149.
Verma Neha Pandit Soumya Gupta Piyush Kumar Kumar Sanjay Kumar Anil Giri Shiv Kumar Yadav Gulab Priya Kanu 《Environmental science and pollution research international》2022,29(21):30954-30966
Environmental Science and Pollution Research - Long-term exposure to organic solvents is known to affect human health posing serious occupational hazards. Organic solvents are genotoxic, and they... 相似文献