Tumor promoting effects of cyanobacterial extracts are potentiated by anthropogenic contaminants--evidence from in vitro study

Inhibition of gap junctional intercellular communication (GJIC) is affiliated with tumor promotion process and it has been employed as an in vitro biomarker for evaluation of tumor promoting effects of chemicals. In the present study we investigated combined effects of anthropogenic environmental contaminants 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB 153) and fluoranthene, cyanotoxins microcystin-LR and cylindrospermopsin, and extracts of laboratory cultures of cyanobacteria Aphanizomenon gracile and Cylindrospermopsis raciborskii, on GJIC in the rat liver epithelial cell line WB-F344. Binary mixtures of PCB 153 with fluoranthene and the mixtures of the two cyanobacterial strains elicited simple additive effects on GJIC after 30 min exposure, whereas microcystin-LR and cylindrospermopsin neither inhibited GJIC nor altered effects of PCB 153 or fluoranthene. However, synergistic effects were observed in the cells exposed to binary mixtures of anthropogenic contaminants (PCB 153 or fluoranthene) and cyanobacterial extracts. The synergistic effects were especially pronounced after prolonged (6-24 h) co-exposure to fluoranthene and A. gracile extract, when mixture caused nearly complete GJIC inhibition, while none of the individual components caused any downregulation of GJIC at the same concentration and exposure time. The effects of cyanobacterial extracts were independent of microcystin-LR or cylindrospermopsin, which were not detected in cyanobacterial biomass. It provides further evidence on the presence of unknown tumor promoting metabolites in cyanobacteria. Clear potentiation of the GJIC inhibition observed in the mixtures of two anthropogenic contaminants and cyanobacteria highlight the importance of combined toxic effects of chemicals in complex environmental mixtures.     

垂管方式对环境监测质量管理体系的建设性意见

实现环境监测领域的垂直管理是国家做出的一项重要决定。这样有利于全面提高环境监测的质量,满足日益严格的环境监测质量工作需求。因此就需要创建出更加优质的环境检测质量管理体系,完善法律法规,利用垂直管理方式来全方位提高工作效果。本文将对利用垂管方式建设环境监测质量管理体系进行深入研究。     

Ethical considerations for community-based participatory research with Sami communities in North Finland

This study examines the perspectives of Sami community members and university researchers regarding the ethical considerations for engagement in Community-Based Participatory Research (CBPR) with Sami communities in northern Finland. Key informant interviews were conducted with Sami people from Finland who were exposed to or participated in research in their communities as well as with researchers who have conducted research with the Sami in Finland across diverse topics. Five themes were identified: establishing trust, research preparation, research comprehension, research ethics, and inclusion in research. The differences in participant perspectives were compared based on their community versus researcher roles. Our findings emphasize the need for (1) strategies to develop and maintain trust between Sami communities and researchers; (2) methods to bridge concepts of bias projected onto Sami communities and researchers by the others’ differing world views and beliefs about research; and (3) increased education in community-engaged methods for social and natural scientists working with Sami communities. This study supports the need for the development of formalized ethical protocols for conducting community-based engaged research with and for Sami people in Finland that ensure mutually beneficial research for all involved.     

增强富拉尔基区可持续发展能力投入机制的研究

本文在富拉尔基区可持续发展能力分析的基础上,提出了投入机制。     

The science and politics of co-benefits in climate policy

The co-benefits concept implies a ‘win–win’ strategy to address two or more goals with a single policy measure. There is much scholarly and policy attention paid to this concept as a way to avoid making trade-offs between developmental and environmental issues. However, there is no review paper that reviews the nature, evolution, strengths and limits of the co-benefits concept in relation to climate change. Hence, this review article addresses the question: What does the literature tell us about the definition, application and use of the co-benefits concept? Using a literature review approach, this article explains the evolution of the co-benefits concept and its strengths and weaknesses. We conclude that while the concept has tremendous advocacy potential in dealing with the problem that the costs and benefits of climate policy are temporally and spatially not aligned, its de facto potential is limited as mostly economists have engaged with this concept, and there is little trans-disciplinary work undertaken that also looks at the politics and institutional aspects of co-benefits. The article thus provides an impetus to rethink current approaches to studying co-benefits and points to the need for inter- and trans-disciplinary research drawing on economic, political and social sciences.     

Energy efficiency: The best immediate option for a secure, clean, healthy future

The imperatives for reducing the world's dependence on fossil and nuclear fuels have multiplied manifold in recent years with the advent of worldwide terrorism. These new dangers come in addition to the imperatives of addressing the dire consequences of global warming and devastating pollution that accompany the use of these fossil fuels. Reducing dependence on these unsafe and unreliable energy resources should be a top global priority. Implementation of proven energy efficiency technologies offers the world the fastest, safest, most economic and most environmentally benign way to alleviate these threats. This article outlines available efficiency measures, their economic advantages and means by which they may be and have been implemented. While examples of efficiency applications from both developed and developing countries are given, the article relies heavily on experience with energy efficiency in the United States, where data on efficiency is particularly abundant.     

上海市环境保护科学研究的回顾与展望

２０年来，上海市已培育、发展、形成了一支稳定的环境科学研究队伍。回顾了这支队伍承担的上海市环保局下达的４７０余项科研项目中，一些主要的课题取得了卓越成果。在回顾的同时，对加强环境保护科研工作提出了五点意见。     

Research core and framework of sustainability science

This paper reviews recent achievements in sustainability science and discusses the research core and framework of sustainability science. We analyze and organize papers published in three selected core journals of sustainability science: Sustainability Science, Proceedings of the National Academy of Sciences of the United States of America, and Sustainability: Science, Practice, & Policy. Papers are organized into three categories: sustainability and its definition, domain-oriented research, and a research framework for sustainability science. First, we provide a short history and define the basic characteristics of sustainability; then we review current efforts in the following research domains: climate, biodiversity, agriculture, fishery, forestry, energy and resources, water, economic development, health, and lifestyle. Finally, we propose a research framework for sustainability science that includes the following components: goal setting, indicator setting, indicator measurement, causal chain analysis, forecasting, backcasting, and problem–solution chain analysis. We emphasize the importance of this last component for improving situations and attaining goals.     

Environmental psychology with a Latin American taste

This paper describes and analyzes the actual and potential contributions of Latin American environmental psychology (EP) to the study of environment–behaviour interactions. Latin America is a richly socoi- and bio-diverse region; the multitude of problems caused by threats to its diversity requires especial conceptual and methodological approaches for studying and solving those problems. Latin American environmental psychologists have contributed ideas and studies according to the specificities (indigenous psychologies) of their nations. These specificities include Latin American traditions of collective participation, holistic worldviews, emotional attachment to places and other individuals, biospheric attitudes and preference for diversity, among others, in addition to the cultural traditions inherited from Europe. These traditions are considered in EP studies conducted by Latin American authors, which are described and commented upon. The importance of formative programs for a professionalizing environmental psychology in the area is discussed. Finally, this paper envisions the future of EP in Latin America. Such a forecast includes our vision of how environmental psychologists in the region could contribute to the general development of a universal environmental psychology.     

Integrative research on environmental and landscape change: PhD students' motivations and challenges

The growing demand for integrative (interdisciplinary or transdisciplinary) approaches in the field of environmental and landscape change has increased the number of PhD students working in this area. Yet, the motivations to join integrative projects and the challenges for PhD students have so far not been investigated. The aims of this paper were to identify the understanding of PhD students with regard to integrative research, their motivations to join integrative projects, their expectations in terms of integration and results, and to reveal the challenges they face in integrative projects. We collected data by a questionnaire survey of 104 PhD students attending five PhD Master Classes held from 2003 to 2006. We used manual content analysis to analyse the free-text answers. The results revealed that students lack a differentiated understanding of integrative approaches. The main motivations to join integrative projects were the dissertation subject, the practical relevance of the project, the intellectual stimulation of working with different disciplines, and the belief that integrative research is more innovative. Expectations in terms of integration were high. Core challenges for integration included intellectual and external challenges such as lack of knowledge of other disciplines, knowledge transfer, reaching depth, supervision, lack of exchange with other students and time demands. To improve the situation for PhD students, we suggest improving knowledge on integrative approaches, balancing practical applicability with theoretical advancement, providing formal introductions to other fields of research, and enhancing institutional support for integrative PhD projects.