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排序方式: 共有80条查询结果,搜索用时 84 毫秒
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Jordan T. Perkins Michael C. Petriello Bradley J. Newsome Bernhard Hennig 《Environmental science and pollution research international》2016,23(3):2160-2172
The pathology of cardiovascular disease is multi-faceted, with links to many modifiable and non-modifiable risk factors. Epidemiological evidence now implicates exposure to persistent organic pollutants, such as polychlorinated biphenyls (PCBs), with an increased risk of developing diabetes, hypertension, and obesity; all of which are clinically relevant to the onset and progression of cardiovascular disease. PCBs exert their cardiovascular toxicity either directly or indirectly via multiple mechanisms, which are highly dependent on the type and concentration of PCBs present. However, many PCBs may modulate cellular signaling pathways leading to common detrimental outcomes including induction of chronic oxidative stress, inflammation, and endocrine disruption. With the abundance of potential toxic pollutants increasing globally, it is critical to identify sensible means of decreasing associated disease risks. Emerging evidence now implicates a protective role of lifestyle modifications such as increased exercise and/or nutritional modulation via anti-inflammatory foods, which may help to decrease the vascular toxicity of PCBs. This review will outline the current state of knowledge linking coplanar and non-coplanar PCBs to cardiovascular disease and describe the possible molecular mechanism of this association. 相似文献
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Effler SW Auer MT Peng F Perkins M O'Donnell SM Prestigiacomo AR Matthews DA DePetro PA Lambert RS Minott NM 《Water environment research》2012,84(3):254-264
Factors that diminish the effectiveness of phosphorus inputs from a municipal wastewater treatment facility (Metro) in contributing to phosphorus levels and its availability to support algae growth in a culturally eutrophic urban lake (Onondaga Lake, NY) were characterized and quantified. These factors included the bioavailability and settling characteristics of particulate phosphorus from this effluent, the dominant form (70%) of phosphorus in this input, and the plunging of the discharge to stratified layers in the lake. Supporting studies included: (1) chemical and morphometric characterization of the phosphorus-enriched particles of this effluent, compared to particle populations of the tributaries and lake, with an individual particle analysis technique; (2) conduct of algal bioavailability assays of the particulate phosphorus of the effluent; (3) conduct of multiple size class settling velocity measurements on effluent particles; and (4) determinations of the propensity of the discharge to plunge, and documentation of plunging through three-dimensional monitoring of a tracer adjoining the outfall. All of these diminishing effects were found to be operative for the Metro effluent in Onondaga Lake and will be integrated into a forthcoming phosphorus "total maximum daily load" analysis for the lake, through appropriate representation in a supporting mechanistic water quality model. The particulate phosphorus in the effluent was associated entirely with Fe-rich particles formed in the phosphorus treatment process. These particles did not contribute to concentrations in pelagic portions of the lake, due to local deposition associated with their large size. Moreover, this particulate phosphorus was found to be nearly entirely unavailable to support algae growth. While substantial differences are to be expected for various inputs, the effective loading concept and the approaches adopted here to assess the diminishing factors are broadly applicable. 相似文献
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A global assessment of chromium pollution using sperm whales (Physeter macrocephalus) as an indicator species 总被引:1,自引:0,他引:1
John Pierce Wise Sr. Roger Payne Sandra S. Wise Carolyne LaCerte James Wise Christy Gianios Jr. W. Douglas Thompson Christopher Perkins Tongzhang Zheng Cairong Zhu Lucille Benedict Iain Kerr 《Chemosphere》2009,75(11):1461-1467
Chromium (Cr) is a well-known human carcinogen and a potential reproductive toxicant, but its contribution to ocean pollution is poorly understood. The aim of this study was to provide a global baseline for Cr as a marine pollutant using the sperm whale (Physeter macrocephalus) as an indicator species. Biopsies were collected from free-ranging whales around the globe during the voyage of the research vessel The Odyssey. Total Cr levels were measured in 361 sperm whales collected from 16 regions around the globe detectable levels ranged from 0.9 to 122.6 μg Cr g tissue−1 with a global mean of 8.8 ± 0.9 μg g−1. Two whales had undetectable levels. The highest levels were found in sperm whales sampled in the waters near the Islands of Kiribati in the Pacific (mean = 44.3 ± 14.4) and the Seychelles in the Indian Ocean (mean = 19.5 ± 5.4 μg g−1). The lowest mean levels were found in whales near the Canary Islands (mean = 3.7 ± 0.8 μg g−1) and off of the coast of Sri Lanka (mean = 3.3 ± 0.4 μg g−1). The global mean Cr level in whale skin was 28-times higher than mean Cr skin levels in humans without occupational exposure. The whale levels were more similar to levels only observed previously in human lung tissue from workers who died of Cr-induced lung cancer. We conclude that Cr pollution in the marine environment is significant and that further study is urgently needed. 相似文献
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Allan J. Perkins Hywel E. Maggs Jeremy D. Wilson 《Agriculture, ecosystems & environment》2008,126(3-4):189-194
To assess the effectiveness of over-winter seed provision by agri-environment schemes, bird use of patches of seed-bearing crops was compared with that of other seed-rich habitats on 53 farms in eastern Scotland over three winters. Seed-bearing crops were the most frequently selected habitat, and held 28% of birds of the 10 species recorded. Outside schemes, cereal stubble was the most selected habitat and held 44% of birds. For nine species, seed-bearing crops were used by more birds than expected from the area of crop available in at least one winter, and five species were more likely to occur in first-winter patches, reflecting a greater abundance of cereal grain than in second-winter patches. For cereal grain specialists such as buntings, sowing cereal-based crops annually would ensure that grain is available in each winter, whilst either a 1-year or a 2-year crop would be appropriate for finches that favour oilseeds, and species with a more generalist diet. 相似文献
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Paul Perkins 《The Environmentalist》1996,16(4):263-268
Summary Environmentally Sensitive Areas were introduced in Britain by the Ministry of Agriculture, Fisheries and Food during 1987. By 1994, the fourth round of designations had brought the total of such areas to 22. The environmental implications for the North Peak, which was designated as such an area in 1988, are discussed in the context of sheep farming and heather management, for these have shaped the patchwork of moorland ecosystems that give the North Peak its unique character.Paul Perkins is a research worker at the University of Huddersfield. He is currently undertaking research into how derelict mining land in West and South Yorkshire can be reclaimed for productive use. 相似文献
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Richard J. Perkins 《Ecological modelling》1978,5(1):1-15
Using a recently developed technique, a realistic method of introducing species into an evolving ecosystem simulation model is presented. A single unit, preemption strength, provides an index which combines strictly preemptive and strictly head-of-the-line colonization strategies. An optimization of priority strategies is presented. The relevance of the realistically evolving model to the stability-complexity problem is emphasized. 相似文献
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E. J. Perkins 《Chemistry and Ecology》1982,1(1):1-32
At a time when scientists contribute to and, at times, seem likely to be overwhelmed by an information explosion, one might pardonably question the need for another journal; particularly another journai of an ecological nature. Too often, however, land, sea and fresh water are treated as if they do not interact, and chemistry, although a driving force in ecological systems, is either viewed as an impact upon parts rather than the whole system, or ignored completely: an attitude which is the despair of chemists and a grave loss to ecologists. Indeed, i t would seem, particularly in the marine field, that biologists/ecologists are falling far behind the chemists and this is a loss to the scientific community as a whole. One outcome is a lack of the wider view and those attempts to theorise which are necessary to progress in the subject. While not forgetting that an understanding of the component parts is vital to an understanding of the whole, Chemistry in Ecology will seek to promote the wider view, and in so doing try to create “bridges” between studies which have not been allied hitherto, but may advantageously work together in the future. 相似文献