Neighborhood Level Spatial Analysis of the Relationship Between Alcohol Outlet Density and Criminal Violence

Misuse of alcohol is a significant public health problem, potentially resulting in unintentional injuries, motor vehicle crashes, drownings, and, perhaps of greatest concern, serious acts of violence, including assaults, rapes, suicides, and homicides. Although previous research establishes a link between alcohol consumption increased levels of violence, studies relating the density of alcohol outlets (e.g., restaurants, bars, liquor stores) and the likelihood of violent crime have been less common. In this paper we test for such a relationship at the small area level, using data from 79 neighborhoods in the city of Minneapolis, Minnesota. We adopt a fully Bayesian point of view using Markov chain Monte Carlo (MCMC) computational methods as available in the popular and freely available WinBUGS language. Our models control for important covariates (e.g., neighborhood racial heterogeneity, age heterogeneity) and also account for spatial association in unexplained variability using conditionally autoregressive (CAR) random effects. Our results indicate a significant positive relationship between alcohol outlet density and violent crime, while also permitting easy mapping of neighborhood-level predicted and residual values, the former useful for intervention in the most at-risk neighborhoods and the latter potentially useful in identifying covariates still missing from the fixed effects portion of the model.     

Genetic variation in defense chemistry in wild cabbages affects herbivores and their endoparasitoids

Populations of wild Brassica oleracea L. grow naturally along the Atlantic coastlines of the United Kingdom and France. Over a very small spatial scale (i.e., <15 km) these populations differ in the expression of the defensive compounds, glucosinolates (GS). Thus far, very few studies have examined interactions between genetically distinct populations of a wild plant species and associated consumers in a multitrophic framework. Here, we compared the development of a specialist (Pieris rapae) and a generalist (Mamestra brassicae) insect herbivore and their endoparasitoids (Cotesia rubecula and Microplitis mediator, respectively) on three wild populations and one cultivar of B. oleracea under controlled greenhouse conditions. Herbivore performance was differentially affected by the plant population on which they were reared. Plant population influenced only development time and pupal mass in P. rapae, whereas plant population also had a dramatic effect on survival of M. brassicae. Prolonged development time in P. rapae corresponded with high levels of the indole GS, neoglucobrassicin, whereas reduced survival in M. brassicae coincided with high levels of the aliphatic GS, gluconapin and sinigrin. The difference between the two species can be explained by the fact that the specialist P. rapae is adapted to feed on plants containing GS and has evolved an effective detoxification system against aliphatic GS. The different B. oleracea populations also affected development of the endoparasitoids. Differences in food-plant quality for the hosts were reflected in adult size in C. rubecula and survival in M. mediator, and further showed that parasitoid performance is also affected by herbivore diet.     

Mandatory child restraint laws: Impact on childhood injuries due to traffic crashes

Research has indicated that laws requiring use of restraint devices for young children traveling in automobiles have had significant effects in increasing restraint use and reducing crash-related childhood injuries. This study examined dimensions along which the effectiveness of Michigan's April 1982 mandatory child restraint law varied. All children involved in motor vehicle crashes in Michigan from January 1978 through December 1982 were analyzed using multivariate intervention analysis methods. Research revealed that the effectiveness of the law in reducing childhood injuries was primarily due to reductions in less severe injuries occurring in crashed vehicles experiencing low to moderate levels of damage. Furthermore, the mechanism for the law's effects was not simply an increase in restraint use. In addition, the number of children riding in the more dangerous front-seat and cargo-area positions apparently decreased following implementation of the law, with children increasingly riding in the safer rear-seat position.     

The legal minimum drinking age in texas: Effects of an increase from 18 to 19

Effects on motor vehicle crash involvement of raising the legal drinking age in Texas from 18 to 19 were examined, using an interrupted time-series design. Rates of single-vehicle-nighttime (SVN) and non-SVN crashes per 100,000 licensed drivers from 1978 through 1984 were examined for three levels of crash severity (serious injury, minor injury, property damage only) and four age groups (16–17, 18, 19–20, 21 and over). Results revealed significant reductions in SVN crashes for the 18-year-old target population across all levels of crash severity: serious injury, down 10.8% ; minor injury, down 14.3% ; and property damage only, down 12.8%. In comparison, no significant changes in SVN crashes among drivers age 21 and over were found. When the effects of macroeconomic conditions on crash rates were controlled statistically, no change in the estimated effect of the legal age law was seen. It is clear that the 1-year increase in legal age in Texas had a significant effect on youth crash involvement.     

Liver histopathology of the sharptooth catfish Clarias gariepinus as a biomarker of aquatic pollution

This paper reports on a comparative perspective of liver histopathological data of the sharptooth catfish Clarias gariepinus. The data was collected from a spectrum of relatively un-impacted and isolated, to polluted, eutrophic freshwater ecosystems. Results were compared between regional areas, by combining data from freshwater systems which has a similar pollution status and/or is located within the same geographical region. Measurements included necropsy observations, semi-quantitative liver histopathology (Liver Index), and selected biometrical indices. The aim was to establish whether the results of these measurements would differ between, and/or reflect the pollution status of, the different freshwater aquatic ecosystems. The histopathological analysis showed a higher prevalence of toxicopathic non-neoplastic, and pre-neoplastic alterations in C. gariepinus from the polluted sites. We also found a significant difference between the Liver Index, hepatosomatic index, and condition factor values of fish inhabiting impoundments known to be polluted, compared to the same species from the selected reference sites. Fish from polluted sites also had more macroscopic liver abnormalities. The results suggest that the liver histopathology of this bio-indicator fish species could be a useful biomarker of freshwater aquatic pollution.     

Effects of legal BAC limits on fatal crash involvement: analyses of 28 states from 1976 through 2002

PROBLEM: Hundreds of laws have been implemented in the United States over the past few decades designed to reduce alcohol-impaired driving and the crashes that often result. One approach has been to lower the legally allowable alcohol concentration for drivers. We examined the effects of changes in legal BAC limit in 28 U.S. states from January, 1976 to December, 2002. METHOD: An interrupted time-series quasi-experimental design was used, incorporating non-alcohol-related crashes as comparisons. Four outcome measures of alcohol-related crash involvement were examined: single-vehicle nighttime, BAC=0.01-0.07, BAC=0.08-0.14, and BAC>/=0.15. Missing BAC test result data were handled by using multiple imputations. Analyses involved estimation of state-specific ARIMA models, controlling for other factors affecting overall crash rates and other major DUI policy changes. Inverse variance weighting methods were used to pool results across states for the most precise underlying estimate of effect of legal BAC limits. RESULTS: Considerable state by state variability in estimated effects was observed, but results from the pooled analyses were clear and consistent. Changes in legal BAC limits significantly affected alcohol-related fatal crash involvement for both the SVN and BAC test result measures, and the laws affected drivers at all drinking levels. SUMMARY: An estimated 360 deaths are prevented each year in the United States as a result of the move from a 0.10 to 0.08 legal limit in recent years, and an additional 538 lives could be saved each year if the United States reduced the limit to 0.05, consistent with limits in most countries worldwide. IMPACT ON INDUSTRY: Given the significant effects of lower legal BAC limits on fatal crash involvement, businesses should support implementation of laws that further reduce the legal BAC limit for all drivers. Furthermore, all companies should set higher standards for employees, such as a zero allowable BAC limit for driving during work time.     

Preventing highway crashes by raising the legal minimum age for drinking: An empirical confirmation

In recent years there has been increased interest in reducing the massive social costs due to alcohol-related motor vehicle crashes. Raising the legal minimum age for purchase and consumption of alcohol beverages has been proposed as one way to reduce alcohol-related crashes among young drivers. Currently, many states are raising the legal age, in contrast to the trend towards lower legal drinking ages in the early 1970s. Recent studies of the effects of raising the drinking age are reviewed, and results from a controlled multiple time-series evaluation of the experience in Michigan are presented. Significant 11 to 28% reductions in alcohol-related crash involvements are shown to be attributable to the raised drinking age in Michigan. Suggestions for further research and discussion of policy implications are included.